-Graviola / Paw Paw should not be used
by anyone who is pregnant, who may be pregnant or who may become pregnant (since
fetal cells are fast-growing).
♦Simple and mild therapy - cancer
patient would not know they were on a potent alternative cancer treatment.
♦The twigs of graviola and paw paw contain
annonaceous acetogenins with
beneficial effects against cancer –acetogenins are long-chained, fatty acid substances with some
very unique properties. Of over 3500 plants screened by a National Cancer
Institute (NCI)-funded project at Pudue University led by Dr. Jerry McLaughlin,
the actegenin compounds of the Annonaceae family had the most anti-cancer
potential. Of these, the paw paw andgraviola plant have especially high concentrations of acetogenins.
1.SLOW DOWN / STOP the
production ofATPenergy molecules in cancer cells(which
produce their energy anaerobically) -
Normal cells (which produce energy aerobically)
are insignificantly affected. When the ATP
production drops to a critical level the
cancer cell dies.
2.Prevents the growth
of vessels in or near a tumor
3.Depletes the DNA
and RNA building blocks necessary for new, abnormal cell division – effective against human CEM cell lines in leukemia;
proven to reduce DNA and RNA production in 3 days.
4.Kills cells that are
resistant to chemotherapy –after some time of being bombarded with chemotherapy drugs, cancer cells self-protectingly develop a mechanism to turn on an
ATP-fueled pump that pumps the chemotherapy
right out of the cancer cells. Paw Paw prevents this from happening .
♦Graviola and Paw Paw work similarly, but there
are some major differences between them:
annonaceae family, but different plants:
is a tropical rainforest South American plant -
its fruit is called guanábana. Common names for it are soursop
(English name), custard apple, cherimoya,and Brazilian paw paw. The fruit, leaves, stem,
bark, roots, and seeds all have a long-standing medicinal use.
Paw species Asimina triloba is found in North America –
cancer treatments use a patented extract of acetogenins from its twigs. There are other species, but only this
species was found to have the cancer-fighting acetigenins.
Of these, threehave been identified as the most bioactively potent -
bullatacin, asimicin, and trilobacin. To correct a common
misconception, paw paw is totally unrelated to papaya.
and Annonaceous acetogenin count convey to Paw Paw a far greater potency than
Graviola(1970’s NCI funded research atPurdue Univ. under Dr. McLaughlin - This man is known for his work with
paw paw and is also an expert on graviola – he not only isolated the acetogenin
compounds in paw paw, but he also found these compounds in graviola, isolating
28 acetogenin compounds during two separate research projects
√Paw paw contains much more potent double-ring
acetogenin compounds –
graviola contains only single-ring and no double-ring compounds, causing them to
have only a fraction of the potency of paw paw.
√50 acetogenins found in paw paw, about 30 in
√Paw Paw extract is 24-50 times more potent than
graviola powder –determined by tests comparing two graviola products with paw
paw extracts carried out under supervision of Dr. McLaughlin. Upjohn Company
(now Pfizer) found paw paw to be 300 times more potent than Taxol (a leading
acetogenin content varies drastically if the product is advertised as “freshly
ground powder” of twigs and leaves - however, if they are not harvested during
the month of May, they are essentially worthless. Also, the acetogenin
potency varies drastically even from tree to tree! Generally, graviola
manufacturers do not standardize their product. BTW, you could make this
yourself if you have access to the graviola plant.
♦A standardized extract from Paw Paw twigs is so
much more potent than graviola, making it the better choice -Dr. McLaughlin, who is now retired,licensed his patents to Nature's Sunshine Products, who sells the product
to the public under the name "Paw Paw
♦Continue to use the program a month after the
cancer tumor markers are all down and there is no further evidence of the cancer
- Then use the program at least once a
month for two to three years.
♦Graviola / Paw Paw is synergistic with
chemotherapy -holding the
chemotoxic drug in the cancer cell longer, allowing it to have more time to do
its work.Graviola has been shown effective against
drug resistant cancer cells.
symptoms E.g. hair loss, bone marrow depression, nausea and
vomiting and itching
(with possible link to Parkinson’s Disease) are carefully excluded from the annonaceous
extracts during processing of paw paw
♦Ongoing studies confirm the benefits of paw paw extracts in clinical
cancer treatments - Paw paw extracts can be
used to inhibit the growth of cancer cells and as effective alternative or
supplement to chemotherapeutic agents. A Malaysial clinical study showed
exceptional results in terminal, metastasized breast cancer patients(i.e. with additional cancers).
♦Research studies show that paw paw extracts have anthelmintic (worm controlling)
What applies to graviola also applies to paw paw
and vice versa
Graviola/Paw Pawcan NOT be used concurrently with a treatment or nutrient
RAISES cellular ATP production:
Electromedicine (e.g. RIFE
RESONANCE PROTOCOL, Beck Protocol), MSM, DMSO, Vitamin C,
Hydrogen Peroxide, maple syrup or honey and some others will nullify
the graviola or paw paw Protocol and vice versa.
Protocols which kill microbes INSIDE cancer cells allow these cells to
produce more ATP energy.
For safety and simplicity
- Do not use the Graviola or Paw
Paw with any other alternative treatment!
♦Graviola has demonstrated hypotensive,
vasodilator, and cardiodepressant activities in animal studies –
graviola (or paw paw)could have adverse consequences for people with low blood
pressure or taking antihypertensive drugs.
♦Should not be taken with any alternative, oxidative (oxidant)cancer
treatment -which would
neutralize the effect of its acetogenins by raising
ATP cellular energy production.
♦Do not take with CoQ10 –
since CoQ10 increases ATP production, it
would interfere with graviola’s mechanism of action of lowering
♦Do not take with thyroid stimulators – E.g. Iodine,which increase
♦New research by the paw paw extract manufacturer
states that combining paw paw withantioxidantsisnot an issue with paw paw -"The head of NSP
research, Dr. Bill Keller, provided Paw Paw with supporting products to a
research oncologist and his laboratory to test with actual cultures. Several of
Nature's Sunshine strong antioxidants were also provided. The research personnel
concluded overwhelmingly that there was no negative prevention of Paw Paw action
as a result of the antioxidants." (Email to CancerTutor.com). Also, see
their videos at:
NOTE HOWEVER, that HIGH doses ofVitamin Cdo not have anantioxidant
effect, they areoxidants
– and as such,should NOT be combined with Graviola or Paw Paw
For simplicity,Do not use Graviola with any other alternative treatment, with the
exception of antioxidants
at physiological levels
♦Do not take Graviola or Paw Paw long-term if no
cancer present – If
cancer, parasites, or other high energy users are not available, Graviola or Paw
Paw may work on fast growing cells lining the GI tract walls. The main
manufacturer of Paw Paw Cell Reg,
Nature's Sunshine, strongly cautions against its long term use for non-cancer
patients. Even some people with cancer have reported digestive distress
includingnausea, which is why the
recommendation that Graviola/Paw Paw should be taken with food.
Technical Mode of Action of Annonaceous acetogenins
Annonaceous acetogenins are only found in the Annonaceae family (to
which Graviola and paw paw belong). Studies in three separate
laboratories have determined that these acetogenins are
superb inhibitors of enzyme
processes that are only found in the membranes of cancerous tumor
Purdue University, West Lafayette, Indiana (much funded by The
National Cancer Institute and/or the National Institute of Health)
has conducted a great deal of the research on acetogenins. Purdue
University and/or its staff have filed at least nine U.S. and
international patents on their work around the anti-tumorous and
insecticidal properties and uses of these acetogenins. In a review
entitled "Recent Advances in Annonaceous Acetogenins", they state:
"Recently, we reported that the
Annonaceous acetogenins can
selectively inhibit the growth of cancerous cells and also inhibit
the growth of adriamycin resistant tumor cells. As
more acetogenins have been isolated and additional cytotoxicity
assays have been conducted, we have noticed that, although most of
acetogenins have high potencies among several solid human tumor cell
lines, some of the derivatives
within the different structural types and some positional isomers
showed remarkable selectivities among certain cell lines;
e.g., against prostate cancer (PC-3). We now understand the primary
modes of action for the acetogenins.
They are potent inhibitors of NADH: ubiquinone oxidoreductase, which is
in an essential enzyme in complex I leading to oxidative
phosphorylation in mitochondria. A recent report showed that they act directly at the
ubiquinone-catalytic site(s) within complex I and in microbial
glucose dehydrogenase. They also inhibit the ubiquinone-linked NADH
oxidase that is peculiar to the plasma membranes of cancerous
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